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PRACA POGLĄDOWA
Wzajemna zależność między zaburzeniami snu a padaczką skroniową – przegląd literatury
 
Więcej
Ukryj
1
Chair and Department of Pathophysiology, Medical University, Lublin, Poland
2
Interdisciplinary Biomedicine Group, Medical University, Lublin, Poland
AUTOR DO KORESPONDENCJI
Barbara Miziak   

Katedra i Zakład Patofizjologii, Uniwersytet Medyczny w Lublinie
 
 
SŁOWA KLUCZOWE
DZIEDZINY
STRESZCZENIE
Wstęp:
Analiza snu i jego faz w kontekście różnych patofizjologii przyciąga coraz większe zainteresowanie środowisk naukowych, dlatego w niniejszym przeglądzie literatury skupiliśmy się na padaczce skroniowej (TLE).

Cel pracy:
Celem tego przeglądu jest usystematyzowanie oraz zaktualizowanie obecnie dostępnej wiedzy i badań na temat wzajemnej zależności deprywacji snu i ataków padaczkowych w TLE, ze szczególnym uwzględnieniem MTLE.

Materiał i metody:
W celu przeszukiwania baz danych Pubmed, Science Direct i Google Scholar użyto następujących kombinacji słów kluczowych: sleep disturbance in mesial temporal lobe epilepsy, sleep in temporal lobe epilepsy, nocturnal temporal lobe epilepsy, temporal epilepsy sleep disturbance. Po zastosowaniu kryteriów wykluczających do przeglądu wybrano 23 artykuły.

Aktualny stan wiedzy:
Zakwalifikowane do przeglądu publikacje zostały podzielone na 7 kategorii na podstawie tematyki publikacji. Wspomniane kategorie dotyczą charakterystycznych fal mózgowych, pamięci i procesów jej konsolidacji, serca i bezdechu sennego, leków przeciwpadaczkowych, zaburzeń motorycznych oraz lateralizacji wyładowań. Artykuły, które nie pasowały tematyką do żadnej z wcześniej wymienionych kategorii, umieszczono w grupie „Inne”.

Podsumowanie:
Sen jest ważnym czynnikiem, który powinien być brany pod uwagę przy doborze odpowiedniego leczenia oraz w badaniach nad nowymi AEDs. Ponadto sen ma istotne znaczenie dla jakości życia pacjenta oraz ma silny wpływ na jego elementy składowe, którymi są np. funkcje fizyczne i społeczne, emocje i wypoczynek, ale także może wpływać na skuteczność terapii.


Introduction:
The analysis of sleep and its phases in the context of various pathophysiologies has attracted increasing attention from the scientific community; therfore, this review of the literature focuses on temporal lobe epilepsy (TLE).

Objective:
The aim of the review is to systematize and update the knowledge and research currently available on the interplay of sleep deprivation and seizures in TLE, with a focus on MTLE.

Material and Methods:
The following keyword combinations were used to search the Pubmed, Science Direct and Google Scholar databases: sleep disturbance in mesial temporal lobe epilepsy, sleep in temporal lobe epilepsy, nocturnal temporal lobe epilepsy, temporal epilepsy sleep disturbance. After applying exclusion criteria, 23 papers were selected for the review.

Brief description of the state of knowledge:
The publications qualified for the review were divided into 7 categories in terms of the subject of the publication. These categories relate to characteristic brain waves, memory and its consolidation processes, heart and sleep apnea, anti-epileptic drugs, motor disorders and lateralization of the discharges. Articles that did not fit into any of the previously mentioned categories were placed in the ‘Other’ group.

Conclusions:
It is agreed that sleep is an important factor that should be taken into account when selecting the appropriate treatment and researching new AEDs. Moreover, sleep is significant to the patient›s quality of life, has a profound impact on its components, for example, physical and social functions, emotions and leisure, but may also influence the effectiveness of therapy.

 
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