Risk factors for contrast induced nephropathy in patients undergoing percutaneous transluminal coronary angioplasty
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Katedra i Klinika Kardiologii Uniwersytetu Medycznego w Lublinie
Samodzielna Pracownia Medycyny Katastrof Uniwersytetu Medycznego w Lublinie
Med Og Nauk Zdr. 2012;18(2):101-105
Introduction and aim of the study:
Contrast-induced nephropathy (CIN) is the third most common cause of acute kidney injury in hospitalized patients, responsible for increased mortality, especially in patients with cardiovascular disease. The aim of this study was to measure the incidence of CIN after elective percutaneous transluminal coronary angioplasty (PTCA) and the potential significance of some factors which are or may be important in the pathogenesis of this complication.

Material and Methods:
The study group included 43 patients, 60 – 80-years-old, an average of 66.36 ± 8.82, with recognized coronary artery disease, undergoing elective PTCA. Renal function was assessed based on the eGFR before and 24 hours after PTCA procedure. The three stages nephropathy grading system (0-I-II) was used.

As many as 29.5% of the patients satisfied CIN criteria. Criterion of a mild (Grade I) nephropathy was found in 20.5% of patients, significant (Grade II) in 9.1% of patients. A slight increase in serum creatinine (Grade 0) was observed in 41.9% of the patients. Statistical analysis showed that age and PTCA within the left main coronary artery (LCA) were independent risk factors for CIN.

Contrast-induced nephropathy is a frequent complication of angioplasty procedures. Older patients and patients undergoing the procedure of PTCA within the LCA require special care during the treatment with the use of contrast.

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