REVIEW PAPER
Inflammation of the choroid plexus and meninges, LCM (Lymphocytic choriomeningitis)
 
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1
Wydział Biologii, Uniwersytet w Lund, Szwecja
2
Zakład Endoskopowych Badań Klinicznych, Instytut Medycyny Wsi, Lublin
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Zakład Epidemiologii Instytut Medycyny Społecznej, Warszawski Uniwersytet Medyczny
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Zakład Alergologii i Zagrożeń Środowiskowych, Instytut Medycyny Wsi, Instytut Medycyny Wsi, Lublin
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Uniwersytet Przyrodniczy, Lublin
CORRESPONDING AUTHOR
Rafał Filip
Zakład Endoskopowych Badań Klinicznych, Instytut Medycyny Wsi w Lublinie, ul. Jaczewskiego 2, 20-090 Lublin
 
Med Og Nauk Zdr. 2012;18(4):416–421
 
KEYWORDS
ABSTRACT
Introduction:
LCM virus belongs to the family Arenaviridae and occurs worldwide. Its reservoirs are small rodents such as mice, rats, hamsters. Humans become infected mainly by inhalation – and therefore the most effective – through dust which contains viruses excreted by apparently healthy, small rodents, or ingestion – eating food contaminated with rodent excreta. The virus penetrates through the mucosa of the upper respiratory tract and gastrointestinal tract and enters the blood, then penetrates through to the brain and other organs. LCM virus infection can lead to inflammation of the choroid plexus and meninges. Infections occur in almost all countries, mostly in the temperate climate, often in spring and autumn. Infection may occur without signs of meninges and brain failure, giving a flu ‑like syndrome. The article presents basic information about the recognition and threats caused by infection with the LCM virus. Key words: LCM virus, human health

 
REFERENCES (23)
1.
Peters CJ. Lymphocytic Choriomeningitis Virus-An Old Enemy up to New Tricks. NEJM. 2006; 354(21): 2208-2211.
 
2.
Mets M B, Barton LL, Khan AS, Ksiazek TG. Lymphocytic choriomeningitis Virus: An Underdiagnosed Cause of Congenital Chorioretinitis. AJO. 2000; 130(2): 209-215.
 
4.
Kańtoch M. Wirusologia lekarska. Warszawa: PZWL; 1998.
 
5.
Kayser FH, Bienz KA, Eckert J, Zinkernagel RM. Mikrobiologia lekarska. Warszawa: PZWL; 2007.
 
6.
Collier L, Oxford J. Wirusologia Podręcznik dla studentów medycyny, stomatologii i mikrobiologii, Wyd. 2 Warszawa: PZWL; 2001.
 
8.
http://www.cdc.gov/ncidod/dvrd... Lymphocytic_Choriomeningitis_Fact_Sheet.pdf.
 
9.
Wright R, Johnson D, Neumann M, Ksiazek TG, Rollin P, Keech RV, i wsp. Congenital Lymphocytic Choriomeningitis Virus Syndrome: A Disease That Mimics Congenital Toxoplasmosis or Cytomegalovirus Infection, Pediatrics. 1997; 100(1).
 
10.
Fischer SA, Graham MB, Kuehnert MJ, Kotton CN, Srinivasan A, Marty FM, Comer JA, i wsp. Transmission of Lymphocytic Choriomeningitis Virus by Organ Transplantation. NEJM. 2006; 354(21): 2235-2249.
 
12.
Jamieson DJ, Kourtis AP, Bell M, Rasmussen SA. Lymphocytic choriomeningitis: an emerging obstetric pathogen. Am J Obstet Gynecol. 2006; 194(6): 1532-1536.
 
13.
Gregg MB. Recent outbreaks of lymphocytic choriomeningitis in the United States of America. Bull World Health Organ. 1975; 52(4-6): 547-553.
 
14.
Childs JE, Glass GE, Korch W, Ksiazek TG, Leduc JW. Lymphocytic Choriomeningitis Virus Infection and House Mouse (Mus Musculus) Distrubution in Urban Baltimore. Am J Trop Med Hyg. 1992; 47(1): 27-34.
 
15.
Laakkonen J, Kallio-Kokko H, Öktem MA, Blasdell K, Plyusnina A, Niemimaa J, Karataş A, Plyusnin A, Vaheri A, Henttonen H. Sero¬logical Survey for Viral Pathogens in Turkish Rodents. JWD. 2006; 42(3): 672-678.
 
16.
Fulhorst CF, Milazzo ML, Armstrong LR, Childs JE, Rollin PE, Khabbaz R, i wsp. Hantavirus and Arenavirus Antibodies in Persons with Occupational Rodent Exposure, North America. EIDJ. 2007; 13(4): 532-538.
 
17.
Tagliapietra V, Rosà R, Hauffe HC, Laakkonen J, Voutilainen L, Vapa¬lahti O, i wsp. Spatial and temporal dynamics of lymphocytic chorio-meningitis virus in wild rodent, nothern Italy. Emerg Infect Dis. 2009; 15(7): 1019-1025.
 
18.
Dobec M, Dzelalija B, Punda-Polic V, Zoric I. High prevalence of antibo¬dies to lymphocytic choriomeningitis virus in murine typhus endemic region in Croatia. J Med Virol. 2006; 78(12): 1643-1647.
 
19.
Moll van Charante AW, Groen J, Osterhaus ADME. Risk of infections transmitted by arthropods and rodents in foresty workers, Brief Report. Eur J Epidemiol. 1994; 10: 349-351.
 
20.
Fiszer U. Zapalenia opon mózgowo-rdzeniowych i mózgu. Prz Lek. 2004; 9(69): 36-42.
 
21.
Taytsch-Kapulkin FZ. Ocena roli etiologicznej wirusa choriomeningitis w neuroinfekcjach w Polsce. Przegl Epidemiol. 1976; XXX(4): 507-510.
 
22.
Piekarska A, Zboińska J, Szymczak W. Ocena diagnozowania etiologii limfocytowych zapaleń opon mózgowych i mózgu u dorosłych w ma¬teriale własnym. Przegl Epidemiol. 2003; 57: 439-447.
 
23.
Stefanoff P, Rosińska M. Zapalenia opon mózgowo-rdzeniowych i zapa¬lenia mózgu w 2005 roku, Przegl Epidemiol. 2007; 61: 225-234.
 
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