RESEARCH PAPER
Should statins be applied in patients with hepatic disease? – Discussion based on case report
| 1 | Z Katedry i Kliniki Chorób Wewnętrznych Uniwersytetu Medycznego w Lublinie |
Med Og. 2010;16(3):361–365
KEYWORDS
ABSTRACT
A patient was admitted to the Clinic due to symptoms of type 2 diabetes and arterial hypertension. Based on the results of laboratory tests and imaging examinations, non-alcoholic fatty liver disease was diagnosed. Despite the features of liver damage the patient was treated with statin. Based on the case presented, indications and contraindications were discussed for the application of statins in patients with liver impairment.
REFERENCES (6)
1.
Abel T., Feher J., Dinja E., Eldin MG, Kovacs A.: Safety and efficacy of combined ezetimibe/simvastatin treatment and simvastatin monotherapy in patients with non-alcoholic fatty liver disease. Med Sci Monit 2009, 15, MS 6-11.
2.
Ahmed MH. Rosuvastin: a safe and effective treatment for dyslipidaemia associated with non-alcoholic steatohepatitis (NASH). Scand J Gastroenterol 2006, 41, 631.
3.
Cohen DE, Anania FA, Chalasani N.: An assessment of statin safety by hepatologists. Am J Cardiol 2006, 97, 77C-81C.
4.
De Denus S., Spinler S.A., Miller K, Peterson AM.: Statins and liver toxicity: a meta-analysis. Pharmacotherapy 2004, 24, 584-591.
5.
Gomez-Dominguez E., Gisbert JP, Moreno-Monteagudo JA, Garcia-Buey L., Moreno-Otero R.: A pilot study of atorvastatin treatment in dyslipemid, non-alcoholic fatty liver patients, Alimentary Pharmacology & Therapeutics 23, 2006, 1643 – 1647.
6.
Smith CC., Bernstein LI., Davis RB., Rind DM., Shmerling RH.: Screening for Statin-Related Toxicity. The Yield of Transaminase and Creatine Kinase Measurements in Primary Care Setting, Arch Intern Med 2003, 163, 688-692.
We process personal data collected when visiting the website. The function of obtaining information about users and their behavior is carried out by voluntarily entered information in forms and saving cookies in end devices. Data, including cookies, are used to provide services, improve the user experience and to analyze the traffic in accordance with the Privacy policy. Data are also collected and processed by Google Analytics tool (more).
You can change cookies settings in your browser. Restricted use of cookies in the browser configuration may affect some functionalities of the website.
You can change cookies settings in your browser. Restricted use of cookies in the browser configuration may affect some functionalities of the website.